Author/Authors :
Bolleku, Eriola University Hospital Center (UHC) “Mother Teresa” - Service of Nephrology, Albania , Idrizi, Alma University Hospital Center (UHC) “Mother Teresa” - Service of Nephrology, Albania , Barbullushi, Myftar University Hospital Center (UHC) “Mother Teresa” - Service of Nephrology, Albania , Bajrami, Valbona University Hospital Center (UHC) “Mother Teresa” - Service of Nephrology, Albania , Likaj, Ermal University Hospital Center (UHC) “Mother Teresa” - Service of Cardiosurgery, Albania , Thereska, Nestor University Hospital Center (UHC) “Mother Teresa” - Service of Nephrology, Albania , Ohri, Ilir University Hospital Center (UHC) “Mother Teresa” - Intensive Care Unit, Albania , Nunci, Lordian University Hospital Center (UHC) “Mother Teresa” - Intensive Care Unit, Albania
Abstract :
Lactic acidosis is a rare but severe complication in patients with type 2 diabetes treated with metformin. Patients with lactic acidosis show commonly signs of shock, tissue hypoxia, acute hepatic or renal failure and the link between metformin therapy and lactic acidosis may be coincidental, associated or causal. Excessive plasma metformin concentrations show that lactic acidosis is due to a toxicological mechanism. We report a case of severe multiorganic failure in a subject after treatment with high doses of metformin.
Keywords :
Metformin , Lactic acidosis , Multiorganic failure , Tissue hypoxia
