Title of article :
HYPOGLYCEMIC EFFECT OF ALOE VERA EXTRACT IN ALLOXAN-INDUCED DIABETIC ALBINO RATS
Author/Authors :
JAFRI, SAGHIR A. The University of Lahore - Institute of Molecular Biology and Biotechnology, Pakistan , HASAN, SYED S. The University of Lahore - Institute of Molecular Biology and Biotechnology, Pakistan , NADEEM, AFTAB Shaukat Khanum Memorial Cancer Hospital and Research Centre - Department of Pathology, Pakistan , KALSOOM The University of Lahore - Institute of Molecular Biology and Biotechnology, Pakistan , IQBAL, JAVED Shaukat Khanum Memorial Cancer Hospital and Research Centre - Department of Pathology, Pakistan
Abstract :
The present study was aimed to evaluate the antidiabetic activity of leaf extract of Aloe vera on forty adult male albino rats weighing 200-300 mg body weight (BW) which were divided into four groups (A, B, C and D), Group A served as control, Group B included normal rats treated with Aloe vera leaf extract (0.5 ml/100 gm BW), Group C and D were made diabetic by alloxan injection (65 mg/100 gm BW). Group C served as diabetic control while Group D was given Aloe vera leaf (AVL) extract at the same dose to Group B for 30 days. After 30 days the blood serum was analyzed for serum glucose level in all the four Groups. Twenty rats were randomly taken from these 40 rats for a follow up study and were not given AV extract. The serum glucose level was significantly (P . 0.05) decreased in AVL extract feeded rats in Group B and D indicating its hypoglycemic effect.
Keywords :
aloe vera , diabetic , albino rats , alloxan
Journal title :
Medical Journal of Islamic World Academy of Sciences
Journal title :
Medical Journal of Islamic World Academy of Sciences
