Title of article :
Antimicrobial Activity of Some New Oxadiazole Derivatives
Author/Authors :
Muhi-eldeen, Zuhair Petra University - School of Pharmacy - Department of Pharmaceutics, Jordan , Juma a, Ghada University of Kufa - College of Pharmacy, Iraq , AI-kaissi, Elham Petra University - College of Pharmacy, Jordan , Nouri, Lina University of Baghdad - College of Pharmacy, Iraq
Abstract :
Alkyl, alkenyl, sulfonyl, thiocarbamates and Mannich derivatives were synthesized and characterized through IR, NMR, and Elemental analysis. It is of interest to report the isomerization rearrangement of propynyl to allene group in Mannich reaction under basic condition. The most promising compound as antibacterial agent was 5-(pyridyl)-1, 3, 4-oxadiazole-2-benzylthiocarbamates.
Keywords :
Mannich derivative , Antibacterial , Isomerization , Propynyl , Allene derivatives.
Journal title :
Jordan Journal of Chemistry
Journal title :
Jordan Journal of Chemistry
