Molecular detection of some virulence gene associated with pathogenicity of Klebsiella pneumoniae

In this study, only seven isolates of Klebsiella pneumoniae were subjected for detection espB, cesT/eae, and CNF1 genes in their genome.It was seen that esp gene was not found in all isolates understudy, whereas cytotoxic necrotizing factor-1(cnf1) was detected in four isolates of Klebsiella pneumoniae. Moreover, three isolates were shown to possess cesT/eae gene in their genome. The presence of such genes will provide the bacteria to invade and evade the host immune system and also will interfere with wound healing as a result of cnf1 production.