Title of article :
SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF SOME NEW SUBSTITUTED 9-(1H/-PYRAZOLO [3,4-b] QUINOLIN-1 - YL) ACRIDINES
Author/Authors :
Thakor, Sanjay Sardar Patel University - Department of Chemistry, INDIA , Parmar, Pankaj Sardar Patel University - Department of Chemistry, INDIA , Patel, Manish Sardar Patel University - Department of Chemistry, INDIA , Patel, Ranjan Sardar Patel University - Department of Chemistry, INDIA
Abstract :
2-Chloro-6-methyl/methoxy-3-formylquinoline upon condensation with substituted 9- hydrazino- acridine afforded corresponding hydrazones which were cyclized under alkaline condition to give 9-(6-substituted-1H-pyrazolo[3,4-b]quinolin-1-yl)acridine analoges. All of the synthesized compounds were characterized by their elemental analysis, IR and NMR spectral studies. Biological screening of the prepared compounds have been screened on some strain of bacteria and fungus.
Keywords :
2 , Chloro , 3 , formyl quinoline , acridines , synthesis , antimicrobial activity
Journal title :
Saudi Pharmaceutical Journal(SPJ)
Journal title :
Saudi Pharmaceutical Journal(SPJ)
