Title of article :
Synthesis of New Glycine Cephalexin Condensed Polymer as Peptide Biopolymer for Controlled Release of Cephalexin
Author/Authors :
K.Al-Saffar ، Aseel K College of Pharmacy - Al-Mustansiriyah University , Abbas ، Ahamed M. Department of Chemistry - College of Science - University of Misan , Salman ، Dawood Department of Chemistry - College of Science - University of Misan
Abstract :
A new peptide-based polymer was synthesized via polymerization of cephalexin acid chloride with glycine acid chloride with molar ratio 1:1 in condensed polymer solution. This Glycine Cephalexin peptide biopolymer was characterized by different analyses of UV, FT-IR and 1H NMR spectroscopy. Also, physical properties of new synthesized Glycine Cephalexin peptide biopolymer were studied with measurement of its intrinsic viscosity at 30°C, swelling percentage in water and studying drug release in pH 4-10 at 37°C.
Keywords :
Glycine , Cephalexin , Biopolymer , characterization , Physical properties
Journal title :
Journal of Chemical Health Risks
Journal title :
Journal of Chemical Health Risks
