Akut Koroner Sendrom Tanısında Yüksek Duyarlılıklı CRP, D-Dimer ve IL-6’nın Duyarlılık ve Seçiciliği

Objective: ACS is the life threatening causes of chest pain. The aim of this study is to detect the sensitivity and specificity of CRP, IL-6 and D-dimer and identify their role in predicting adverse cardiac events. Material and Methods: All patients describing typical chest pain were enrolled in the study. Demographic features and final diagnosis were writ- ten and serum specimens were collected. All patients were telephoned after one month to determine if there were any adverse cardiac events. Results: There were 132 patients, (94 male, 38 female). The mean age was 60.92±10.78. 55 patients were diagnosed as AMI (37 STEMI and 18 NSTEMI) 60 patients as unstable angina pectoris, 15 patients as stable angina pectoris and 2 patients as non cardiac chest pain. 6 patients died in the hospital. 15 patients had adverse cardiac events (12 recurrent AMI, 2 sudden cardiac death, 1 stroke). The levels of D-dimer, CRP and IL-6 at the presentation were not predictive for adverse events. Conclusion: D-dimer, CRP and IL-6 levels were high both in ACS and sta- ble angina. Detecting the predictive value for adverse cardiac events re- quires larger patient numbers and longer follow up times.