Title of article :
Physical and chemical properties of nano-liposome, application in nano medicine
Author/Authors :
Eskandari, Vahid University of Kashan - Kashan, Iran , Sadeghi, Mohammadreza University of Linköping - Linköping, Sweden , Hadi, Amin Yasuj University of Medical Sciences - Yasuj, Iran
Abstract :
The liposome is derived from two Greek roots: 'Lipo' meaning fat and 'Some' meaning
structure. Liposomes can be made from natural phospholipids and cholesterol and, if
necessary, other additives. Liposomes were first discovered by Bangham in 1961 due to
their simple, self-fulfilling structure and low cost. Liposomes are spherical vesicles with a
membrane composed of bilayer phospholipids that are used to release drugs or genetic
material into the cell. Current research is focused on liposome technology based on the
preparation and development of long-circulating liposomes, lipid components' changing,
and vesicles' charge amount. Liposomes, in addition to pharmaceutical carriers, are used
in cutaneous, respiratory, food industries, injectable, and in genetic engineering and
diagnostic applications. This paper reviews the physical and chemical characteristics,
structure, construction methods, and applications of nanoliposomes in various uses as
drug carriers, including the treatment of specific diseases.
Keywords :
Nanoliposomes , Nanoliposomes fabrication methods , Nanoliposomes applications , Characteristics of nanoliposomes
Journal title :
Journal of Computational Applied Mechanics