Author/Authors :
Taghizadeh, Mohammad Javad Department of Chemistry - University of Imam Hossein, Tehran, Iran , Malakpouri, Gholam Reza Department of Chemistry - University of Imam Hossein, Tehran, Iran , Ghalkhani, Masoumeh Faculty of Science - Shahid Rajaee Teacher Training University, Lavizan, Tehran, Iran
Abstract :
In this research, an efficient synthesis of oxazolam analogues with a number of advantages such as fast and cheap production procedure with great yields was presented. The purpose of this investigation was to develop a more economical and technically more feasible route to synthesis of oxazolam analogues. Aminobenzophenone was acylated to give corresponding amides. The ring forming reaction of amides with the appropriate amino (alcohol or thiol) produced oxazolam analogues with 83-98 % total yield.The structures of synthesized compounds were characterized by recording their IR,1H NMR, 13C NMR, and mass spectra.
