Title of article
تطوير طريقة طيفية مباشرة لتقدير الكلوربرومازين في المستحضرات الصيدلانية باستخدام مبادلات ايونية لازالة المتداخلات
Author/Authors
قاسم, بشرى بشير جامعة بغداد - كلية العلوم - قسم الكيمياء, العراق
Pages
9
From page
1
To page
9
Abstract
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Other languages abstract
In this scientific piece of research work, chlorpromazine CPZ (a psychaity drug) was determined spectrophotometrically using micro amount of reactant.
In addition to micro amount of spectrophotometric reagent (400 ^l).
Various oxidizing agents were tested, including periodate, iodate, bromate, ferric nitrate, ferri cynate and persulphate.
Oxidation reactions of the active ingradient (2,10-disubstituted phenothiazine) was used for the determination of CPZ in the presence of ferric nitrate.
Detailed study of all chemical and physical parameters were studied.
Ion-exchange columns were used to overcome the interfering ions.
Percentage linearity was 99.86 for 0.04-8 mM CPZ, L.O.D.
was 1x106M.
Repeatabilety was better than 1.5%.
The established results were followed to determine in some drugs.
Keywords
طريقة طيفية مباشرة , تقدير الكلوربرومازين , المستحضرات الصيدلانية , مبادلات ايونية , لازالة المتداخلات
Journal title
Baghdad Science Journal
Serial Year
2008
Journal title
Baghdad Science Journal
Record number
2688379
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