Embryological developmental changes in the gonads of male mice associated with lead administration

The biological systems of human in the modern world are increasely being exposed to lead which exists in the environment. Women at reproductive age and pregnant are more susceptible to the danger of environmental lead pollutant leading to infertility. Prenatal exposure to lead may cause abnormal growth, spontaneous abortion and congenital problems. As there is an increase usage of electrical generators that depend on lead-based gasoline by Iraqi people which lead to increase the air pollution with this toxic substance induced us to detect through this study its possible negative effects on the fate of conception and embryonic development using the mouse as a model. The study aims to asses the effect of low dose concentrations of lead acetate given to pregnant female mice on the development of gonads of male mice embryos at different periods of gestation. Mature mice aging 8-10 weeks(180 mice) weighing 25-27 grams were used.