Title of article
Chloroquine-induced Acute Dystonic Reactions after a Standard Therapeutic Dose for Uncomplicated Malaria
Author/Authors
Busari, Olusegun A. Federal Medical Centre - Department of Internal Medicine, Nigeria , Fadare, Joseph Federal Medical Centre - Department of Internal Medicine, Nigeria , Agboola, Segun Federal Medical Centre - Departments of Family Medicine, Nigeria , Gabriel, Olusegun Federal Medical Centre - Departments of Family Medicine, Nigeria , Elegbede, Olayide Federal Medical Centre - Departments of Family Medicine, Nigeria , Oladosu, Yusuf Federal Medical Centre - Departments of Family Medicine, Nigeria
From page
476
To page
478
Abstract
Acute dystonic reactions (ADR) are extrapyramidal effects that usually occur after the initiation of awide variety of drugs or triggering factors besides neuroleptics. We report the case of a 54-year-old man who was admitted with an approximately 10-hour history of muscle twitching around the eyes, face and neck after he took the first dose of oral chloroquine phosphate (1 g [600 mg base]) prescribed for uncomplicated malaria. He was given intravenous diazepam (10 mg statum) followed by 10 mg of oral diazepam 3 times a day. The symptoms improved within 30 minutes of treatment, and he was discharged 14 hours later after a complete recovery.
Keywords
Dystonia , Reactions, acute , Malaria , Chloroquine , Administration, Oral , Case Report , Nigeria
Journal title
Sultan Qaboos University Medical Journal (SQUMJ)
Journal title
Sultan Qaboos University Medical Journal (SQUMJ)
Record number
2690803
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