Title of article
Spectrophotometric Determination of Paracetamol in bulk and Pharmaceutical Preparations
Author/Authors
ahmed, rafah k. university of baghdad - college of science for women - department of chemistry, Baghdad, Iraq , muhammad, saud s. university of baghdad - college of science for women - chemistry department, Baghdad, Iraq , khodaer, enaas a. university of baghdad - college of science for women - chemistry department, Baghdad, Iraq
From page
317
To page
323
Abstract
A simple, and rapid spectrophotometric method for the estimation of paracetamol has been developed. The methods is based on diazotisation of 2,4-dichloroaniline followed by a coupling reaction with paracetamol in sodium hydroxide medium. All variables affecting the reaction conditions were carefully studied. Beer s law is obeyed in the concentration range of 4-350 μgml−1 at 490 nm .The method is successfully employed for the determination of paracetamol in pharmaceutical preparations. No interferes observed in the proposed method. Analytical parameters such as accuracy and precision have been established for the method and evaluated statistically to assess the application of the method.
Keywords
Spectrophotometric determination , Paracetamol , Diazotisation
Journal title
Baghdad Science Journal
Journal title
Baghdad Science Journal
Record number
2691624
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