Author/Authors :
Uçar, Hakan Adana Numune Training and Research Hospital - Clinic of Cardiology, Turkey , Gür, Mustafa Adana Numune Training and Research Hospital - Clinic of Cardiology, Turkey , Gözükara, Mehmet Yavuz Mersin State Hospital - Clinic of Internal Medicine, Turkey , Kıvrak, Ali Adana Numune Education and Research Hospital - Department of Cardiology, Turkey , Kolcu, Zekeriya Van Training and Research Hospital - Clinic of Cardiology, Turkey , Akyol, Selehattin Adana Numune Training and Research Hospital - Clinic of Cardiology, Turkey , Kaypaklı, Onur Adana Numune Training and Research Hospital - Department of Cardiology, Turkey , Elbasan, Zafer Adana Numune Training and Research Hospital - Clinic of Cardiology, Turkey , Şahin, Durmuş Yıldıray Adana Numune Training and Research Hospital - Clinic of Cardiology, Turkey , Türkoğlu, Caner Adana Numune Education and Research Hospital - Department of Cardiology, Turkey , Şeker, Taner Adana Numune Training and Research Hospital - Clinic of Cardiology, Turkey , Çaylı, Murat Adana Numune Training and Research Hospital - Clinic of Cardiology, Turkey
Abstract :
Objective: Morning blood pressure surge (MBPS) is an independent predictor of atherothrombotic cardiovascular events in hypertensive patients. There is evidence from studies supporting the validity of mean platelet volume (MPV) as a marker of vascular risk and predictor of thrombotic complications. The aim of this study is to investigate the relationship between MPV and MBPS in hypertensive patients. Methods: Measurements were obtained from 298 patients with newly diagnosed essential hypertension (Mean age: 51.9±11.7 years). The patients were divided into two groups (MPV_low group; 10.8 fL, MPV_high group; ≥10.8 fL). The MBPS was calculated as mean systolic BP during the 2 hours after awaking minus the mean systolic BP during the 1 hour that included the lowest sleep BP. Results: MPV was independently associated with MBPS (β=0.554, p 0.001) and hs-CRP level (β=0.286, p 0.001). Conclusion: Finally, higher MPV values related to enhanced MBPS which are associated with atherothrombotic cardiovascular events.
