Title of article :
Reference Ranges of Lymphocyte Subsets of Healthy Adults in Turkey
Author/Authors :
Yaman, Akgün Çukurova University - Facultyof Medicine - Department of Microbiology, Turkey , Çetiner, Salih Çukurova University - Faculty of Medicine - Departments of Physiology, Turkey , Kibar, Filiz Çukurova University - Faculty of Medicine - Department of Microbiology, Turkey , Ta s¸ova, Ye s¸im Çukurova University - Faculty of Medicine - Departments of Infectious Diseases, Turkey , S¸eydao g˘lu, Gül s¸ah Çukurova University - Faculty of Medicine - Departments of Biostatistics, Turkey , Dündar, ismail H. Çukurova University - Faculty of Medicine - Departments of Infectious Diseases, Turkey
Abstract :
The aim of this study was to determine the reference ranges of lymphocyte subsets in serologically HIV-negative healthy adults in Turkey. Materials and Methods: Blood samples from 220 healthy adults, 105 female and 115 male, collected into tubes containing EDTA were investigated for lymphocyte subsets using flow cytometry. The age range was 18–80 years (44.80 ± 16.69). Results: The mean percentage and absolute values of the lymphocyte subsets were as follows: CD3: 72.70 ± 8.44%, 1,680 ± 528 cells/μl; CD4: 47.37 ± 9.10%, 1,095 ± 391 cells/μl; CD8: 28.99 ± 5.99%, 669 ± 239 cells/μl; CD19: 10.96 ± 4.44%, 254 ± 122 cells/μl and CD56: 7.03 ± 3.26%, 161 ± 92 cells/μl, respectively. The ratio of CD4/CD8 was 1.68 ± 0.43. There was no statistically significant difference in the percentages and absolute values of lymphocyte subsets between the genders (p 0.05). Conclusion: Immunophenotyping has been used to establish reference values of lymphocyte subsets in normal healthy adults in Turkey.
Keywords :
Lymphocyte subsets , Healthy adults , Flow cytometry
Journal title :
Medical Principles and Practice
Journal title :
Medical Principles and Practice
