Letter to the Editor: Re: Erythropoietin Ameliorates Oxidative Stress and Tissue Injury following Renal Ischemia/Reperfusion in Rat Kidney and Lung

Dear Editor, We read with interest the recently published article by Ardalan et al. in Medical Principles and Practice entitled ‘Erythropoietin ameliorates oxidative stress and tissue injury following renal ischemia/reperfusion in rat kidney and lung . They showed that erythropoietin (EPO) pretreatment could be effective in reducing renal and lung injury following renal ischemia/reperfusion and could improve the cellular antioxidant defense system. We congratulate them for their work; however, we would like to point out some other aspects of kidney-protective effects of erythropoietin. Intraperitoneal administration of EPO after gentamicin administration (100 mg/kg) reversed the increased serum creatinine and blood urea nitrogen.