Author/Authors :
Ağaç, Mustafa Tarık Ahi Evren Cardiovascular and Thoracic Surgery Training and Research Hospital - Department of Cardiology, Turkey , Korkmaz, Levent Ahi Evren Cardiovascular and Thoracic Surgery Training and Research Hospital - Department of Cardiology, Turkey , Bektas, Hüseyin Ahi Evren Cardiovascular and Thoracic Surgery Training and Research Hospital - Department of Cardiology, Turkey , Acar, Zeydin Ahi Evren Cardiovascular and Thoracic Surgery Training and Research Hospital - Department of Cardiology, Turkey , Erkan, Hakan Ahi Evren Cardiovascular and Thoracic Surgery Training and Research Hospital - Department of Cardiology, Turkey , Kurt, Ibrahim Halil Adana Numune Training and Research Hospital - Department of Cardiology, Turkey , Adar, Adem Ahi Evren Cardiovascular and Thoracic Surgery Training and Research Hospital - Department of Cardiology, Turkey , Çelik, Şükrü Ahi Evren Cardiovascular and Thoracic Surgery Training and Research Hospital - Department of Cardiology, Turkey
Abstract :
Objective: To investigate the presence of myocardial fibrosis determined by fragmented QRS in patients with severe aortic valve stenosis. Subjects and Methods: Eighty-seven consecutive patients with severe aortic valve stenosis and 83 age- and gender-matched control subjects were enrolled into this study. Severe aortic valve stenosis was defined as an aortic valve area 1 cm2, a Vmax 4 m/s, or a mean gradient ≥40 mm Hg. Fragmented QRS was assessed using a 12-lead electrocardiogram. Results: Fragmented QRS was detected in 40 (46%) patients in the aortic valve stenosis group and in 15 (18%) control subjects (p 0.001). In multivariate binary logistic regression analysis, the presence of aortic valve stenosis was the only independent factor associated with fragmented QRS (OR = 3.69; 95% CI 1.81-7.55, p 0.001). Conclusion: A higher frequency of fragmented QRS was detected in patients with severe aortic valve stenosis compared to controls.
