Immunohistochemistry of Epithelioid Soft Tissue Sarcomas, Literature Review Based on Case Studies

Neoplasms with epithelioid histology may be diagnostically challenging. Immunohisto chemistry (IHC) can aid in confirming the differential diagnosis of mesotheliomas, melanomas, lymphomas, and soft tissue sarcomas, all tumors that can present with an epithelioid histology. Immunohistochemistry can also assist in confirming the type of sarcomas. Using cases diagnosed in a community hospital setting over a ten year period, the use of IHC in sarcomas will be illustrated