Author/Authors :
Cao, Ruijie Department of Immunology and Rheumatology - The Fourth Hospital of Hebei Medical University, Shijiazhuang, China , Zhang, Shasha Department of Immunology and Rheumatology - The Fourth Hospital of Hebei Medical University, Shijiazhuang, China , Li, Jing College of Integrated Chinese and Western Medicine - Hebei Medical University, Shijiazhuang, China , Zhang, Jingjing Department of Immunology and Rheumatology - The Fourth Hospital of Hebei Medical University, Shijiazhuang, China , Zhao, Yufei Department of Immunology and Rheumatology - The Fourth Hospital of Hebei Medical University, Shijiazhuang, China , Jiao, Pengqing Department of Immunology and Rheumatology - The Fourth Hospital of Hebei Medical University, Shijiazhuang, China , Wang, Cuiju Department of Gynaecology Ultrasound - The Fourth Hospital of Hebei Medical University, China , Guo, Zhanjun Department of Immunology and Rheumatology - The Fourth Hospital of Hebei Medical University, Shijiazhuang, China
Abstract :
Introduction: Chinese herbal medicine (CHM) has been widely used by patients in China and results in unpredictable nephrotoxicity
and hepatotoxicity effects.
Case Presentation:We report the case of a postoperative 69-year-old female patient with ascending colon cancerwhorapidly developed
liver cirrhosis after 18 months of continued CHM administration. The patient underwent right hemicolectomy at the Fourth
Hospital of Hebei Medical University in August 2019 due to ascending colon cancer; at that time, the patient had no signs of liver
cirrhosis based on computed tomography (CT) and routine blood examination. Postoperatively, the patient continuedCHMadministration
for 18 months. The patient then visited our hospital with complaints of jaundice, abdominal distension, and edema in
both lower limbs. CT imaging showed cirrhosis of the liver, while gastroscopy showed mild esophageal varices. Blood examinations
including routine blood, coagulation function, and liver function tests, and biomarkers of hepatic fibrosis also supported the
diagnosis of liver cirrhosis. To the best of our knowledge, this is the first report of CHM-induced liver cirrhosis.
Conclusions: CHM administration possibly induces rapid liver cirrhosis within 18 months
Keywords :
Herbal Medicine , Liver Cirrhosis , Neoplasms , Jaundice
