Author/Authors :
belhani, b. annaba university - laboratory of applied organic chemistry lcoa, synthesis of biomolecules and molecular modeling group, Annaba, Algeria , bechlem, k. annaba university - laboratory of applied organic chemistry lcoa, synthesis of biomolecules and molecular modeling group, Annaba, Algeria , grib, i. annaba university - laboratory of applied organic chemistry lcoa, synthesis of biomolecules and molecular modeling group, Annaba, Algeria , cheloufi, h. annaba university - laboratory of applied organic chemistry lcoa, synthesis of biomolecules and molecular modeling group, Annaba, Algeria , bouasla, r. annaba university - laboratory of applied organic chemistry lcoa, synthesis of biomolecules and molecular modeling group, Annaba, Algeria , berredjem, m. annaba university - laboratory of applied organic chemistry lcoa, synthesis of biomolecules and molecular modeling group, Annaba, Algeria
Abstract :
An easy and handy synthesis of α-sulfamidophosphonates directly by Three- Component reactions is reported. The reaction involves the use of aldehyde, sulfonamides and trimethylphosphite. A wide range of substrates is compatible in this reaction, producing excellent yields in short time. The reaction is performed under solvent- and catalyst-free conditions using microwave irradiation, greener conditions and lower generation of waste or pollution are the main advantages of this method.
Keywords :
Three , component reaction , Microwave , α , sulfamidophosphonates , Green Chemistry
