Author/Authors :
baddade, l. sultan moulay slimane university - faculty of science and technology - transdisciplinary team of analytical sciences for sustainable development, laboratory of applied spectroscopy and chemometrics, Beni Mellal, Morocco , elbir, m. sultan moulay slimane university - faculty of science and technology - transdisciplinary team of analytical sciences for sustainable development, Beni Mellal, Morocco , mbarki, m. sultan moulay slimane university - faculty of science and technology - transdisciplinary team of analytical sciences for sustainable development, Beni Mellal, Morocco , elhadri, i. sultan moulay slimane university - faculty of science and technology - laboratory of applied spectroscopy and chemometrics, Beni Mellal, Morocco , berkani, m. sultan moulay slimane university - faculty of science and technology - laboratory of applied spectroscopy and chemometrics, Beni Mellal, Morocco
Abstract :
The aim of this work was to evaluate the in vitro anti-lithiasic effectiveness of aqueous extract obtained from pulp of Zizyphus Lotus fruits in urine of lithiasic patients so as to valorize it within the framework of sustainable regional development and as local product. So, aqueous extracts of pulp of Z. Lotus fruits were prepared at different concentrations (1-10 mg/ml), submitted to a cold maceration during 48 hours. The crystallization of calcium oxalate was induced in human urine with extract. The study of the crystallization of calcium oxalate is carried out using optical microscope with polarized light (OMPL).The in vitro anti-lithiasic activity was evaluated against aggregation of calcium oxalate. The results show that adding the aqueous extract to the urine will decrease the size and the number of calcium oxalate also Z. Lotus showed in vitro anti-lithiasic activity by inhibiting the aggregation of calcium oxalate.
Keywords :
Valorization , Zizyphus Lotus , Anti , lithiasic Activity , Sustainable Regional Development , Local products
