Title of article :
An HIV-1 PositiveWoman Without Usual Immunodeficiency
Author/Authors :
Moradi, Bagher Department of Basic Sciences - Esfarayen Faculty of Medical Sciences , Keshvari, Saeed Department of Health Sciences - Esfarayen Faculty of Medical Sciences
Abstract :
Introduction: Acquired immune deficiency syndrome (AIDS) inflicts severe damage to the immune system. It is transmitted from
one person to another through blood transfusion and vertical and sexual transmission. It should be noted that almost all papers
reporting AIDS emphasized that HIV led to immune deficiency. However, this study reported the first HIV-1 seropositive woman who
had an active viral load of HIV-1 without any signs or CD4 lymphocyte count depletion.
Case Presentation: This study reported a 46-year-old HIV-1 seropositivewomanwithout any signs and symptoms diagnosed 31 years
ago by laboratory tests. Also, it is noteworthy that the patient had not received regular therapeutics during the infection period. Our
serologic tests showed an active seropositive patient without any CD4 depletion. The viral load of HIV-1 was 132967.2 u/L, which was
quantified by a real-time PCR assay. Also, a CBC test was performed and showed no abnormal results.
Conclusions: An untreated HIV-1 positive patient without immunodeficiency is a rare condition, and we found no report of it in the
literature. This article reported an HIV-1 positive patient inwhomthe infection was confirmed several times using the real-time PCR
method.
Keywords :
HIV-1 , Infection , Lymphocyte , Women , Therapeutics
Journal title :
Archives of Clinical Infectious Diseases