Author/Authors :
Forouzannia, Mohammad Multiple Sclerosis Research Center - Neuroscience institute - Tehran University of Medical Sciences, Tehran , Yarahmadi, Pourya Multiple Sclerosis Research Center - Neuroscience institute - Tehran University of Medical Sciences, Tehran , Alirezaei, Mohammad Multiple Sclerosis Research Center - Neuroscience institute - Tehran University of Medical Sciences, Tehran , Rezaeimanesh, Nasim Multiple Sclerosis Research Center - Neuroscience institute - Tehran University of Medical Sciences, Tehran , Naser Moghadasi, Abdorreza Multiple Sclerosis Research Center - Neuroscience institute - Tehran University of Medical Sciences, Tehran
Abstract :
Background: Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune
astrocytopathic disease affecting central nervous system (CNS). CSF pressure in these
patients is usually normal.
Case Presentation: A 30-year-old woman was admitted with complaints of headache and
lower limbs paresis. Lumbar puncture (LP) and magnetic resonance imaging were
performed for the patient. Opening pressure was 42 cm H2O in the first LP. According to
the clinical evidences, imaging, and the patient's positive aquaporin-4 antibody, the
diagnosis of NMOSD was established.
Conclusion: High intracranial pressure headache; however rare, may be the first sign of the
onset of the acute exacerbation phase of NMOSD
