Author/Authors :
Moghaddam, Yousef Mazandaran University of Medical Sciences, Sari , Ziaei Hezarjaribi, Hajar Pediatric infectious Disease Research Center - Communicable Disease Institute - Department of Parasitology School of Medicine - Mazandaran University of Medical Sciences, Sari , Fakhar, Mahdi Toxoplasmosis Research Center - Communicable Diseases Institute - Iranian National Registry Center for Lophomoniasis and Toxoplasmosis, Department of Parasitology - School of Medicine - Mazandaran University of Medical Sciences, Sari , Pagheh, Abdol Sattar Infectious Diseases Research Center - Birjand University of Medical Sciences, Birjand , Saberi, Reza Parasitology - Student Research Committee - Mazandaran University of Medical Sciences, Sari , Sharbatkhori, Mitra Laboratory Sciences Research Center - Golestan University of Medical Sciences, Gorgan , Ghalehnoei, Hossein Department of Medical Biotechnology - School of Advanced Technologies in Medicine Molecular and Cell Biology Research Center - Mazandaran University of Medical Sciences, Sari , Nazar, Eisa Student Research Committee - Department of Biostatistics - School of Health - Mashhad University of Medical Sciences, Mashhad , Rahimi Esboei, Bahman Department of Parasitology and Mycology - School of Medicine - Islamic Azad University Tonekabon Branch, Tonekabon
Abstract :
Human blood parasites are one of the most critical infections in human that
transmit by vectors. Reservoirs of the parasites are crucially important in the
epidemiology and control. In the current study isolated parasites from a Rhombomys
Optimus (R. opimus), rodent confirms that Crithidia is a zoonotic parasitic disease.
This study aimed to find the high-risk areas of this infection by considering the
distribution of reservoirs and human infection. In this study, 148 rodents from an
endemic focus of Gonbad-e-Qabus city in Golestan province were trapped and then
killed ethically and direct smear and culture in Novy- MacNal-Nicolle medium
(NNN) were taken and finally, results were confirmed by Polymerase Chain
Reaction (PCR) and Sequencing method. Out of 148 rodent, 97 (65.54%) rodent
were male and 51 (34.45%) were female (P <0.05). and in smear and culture were
found 8 (5.40%) T. lewisi, 6 (4.05%) L. major, and 2 (1.35%) Crithidia spp. Based
on the time; 40 (27.02%), 50 (33.78%), 38 (25.67%), and 20 (13.51%) rodents were
trapped in spring, summer, fall, and winter, respectively. Due to northeastern Iran
(Gonbad-e-Qabus) being the endemic focus of cutaneous leishmaniasis (CL), it
should be noted that the reservoirs of this disease may also be contaminated with
Leishmania spp, and Crithidia. Results showed that R. opimus are the important
reservoirs of CL in northeastern of Iran. Important foci of the diseases in almost all
areas of Iran are dispersed. Therefore, reliable methods to control mice are
essentially needed.
Keywords :
Rhombomys opimus , Crithidia, Rodent , Blood parasite
