Author/Authors :
Hatamabadia, Dara Department of Medicinal Chemistry - School of pharmacy - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Mostafizb, Bahar Department of chemistry - Faculty of Physics and Chemistry - University of Alzahra, Vanak, Tehran, Iran , Dowlati Beiramia, Amirreza Department of Medicinal Chemistry - School of pharmacy - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Bananc, Kamran Department of Pharmaceutics - School of Pharmacy - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Sharafi Tafreshi Moghaddamc, Niloufar Department of Pharmaceutics - School of Pharmacy - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Afshararaa, Hanif Department of Medicinal Chemistry - School of pharmacy - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Keçilid, Rüstem Yunus Emre Vocational School of Health Services - Department of Medical Services and Techniques - Anadolu University, Eskişehir, Turkey , Ghorbani-Bidkorbehc, Fatemeh Department of Pharmaceutics - School of Pharmacy - Shahid Beheshti University of Medical Sciences, Tehran, Iran
Abstract :
The process of matrix clean-up and extraction of analytes has a significant influence on the
detection and determination of the analyte, especially in trace amounts. Molecularly imprinted
polymers (MIPs) are solid particles that can absorb specific molecules regarding the template
molecule used in the synthesis process of each type of MIP. As a result, they can be used in more
effective and more specific solid-phase extraction processes. On the other hand, mycotoxins are
second metabolites of molds and fungus which are potentially cytotoxic and/or genotoxic even in
trace amounts, and due to extensive consumption of cereals and the great concern of public health,
several methods were developed and currently are in the process of development to detect and
determine the presence and amounts of mycotoxins in cereals. This review is aimed to investigate
the application and efficacy of MIPs in detecting and determination of mycotoxins in cereals.
Keywords :
Cereal , Molecularly Imprinted Polymer , Detection , Determination , Mycotoxins
