Title of article :
Catalyst free synthesis of spiro derivatives of isatin using multicomponent reactions
Author/Authors :
Sharifi, Samaneh Sadat Department of Chemistry - Faculty of Sciences - Sistan and Baluchestan University, Sistan and Baluchestan , Khandan, Samira Department of Chemistry - Tarbiat Modares University, Tehran , Ghazanfarpour, Majid Department of Chemistry - Faculty of Sciences - Sistan and Baluchestan University, Sistan and Baluchestan
Abstract :
The reaction of aniline, oxalylchloride, malononitrile, activated acetylenic compounds and PPh3 led to spirocompounds of isatines in excellent yields under solvent free conditions at room temperature
Keywords :
Acid chlorides , Ammonium thiocyanate , N-formylmorpholine , 3-Hydroxy-2-butanone , Esterification
Journal title :
Iranian Journal of Organic Chemistry