Title of article :
A synthesis of isatin phosphonate from the reaction of aniline with activated acetylenic compounds in the presence of phosphites
Author/Authors :
Haerizadeh, Bibi Narjes Department of Chemistry - Tarbiat Modares University, Tehran , Koohi, Maryam Department of Chemistry - Tarbiat Modares University, Tehran
Abstract :
The reaction of activated acetylenic compounds with trialkyl(aryl) phosphites in the presence of aniline and diethyl
oxalate leads to stable phosphonate derivatives in excellent yields. The reaction workup is easy and the products can be easily
separated from the reaction mixture.
Keywords :
Acetylenic esters , Phosphites , Phosphonates , Isatin , Three-component reaction
Journal title :
Iranian Journal of Organic Chemistry
