Title of article :
Determining the Amount of Metronidazole Drug in Blood and Urine Samples With the help of PbS Sensor functionalized With Gelatin as a Fluorescence- Enhanced Probe
Author/Authors :
Bouroumand, Shirin Department of Chemistry - Islamic Azad University Omidiyeh Branch, Omidiyeh , Marahel, Farzaneh Department of Chemistry - Islamic Azad University Omidiyeh Branch, Omidiyeh , Khazali, Fereydoon Department of Chemistry - Islamic Azad University Omidiyeh Branch, Omidiyeh
Abstract :
Fluorescent chemical sensors to detect drugs, by increasing fluorescence emission and absorption or by shutting
down, because they are non-destructive, the ability to show decomposed concentrations, fast response, high
accuracy have been considered and used. In this research, a chemical sensor was synthesized PbS functionalized
with gelatin quantum dots for (MNZ) drug. The calibration curve was linear in the range of (0.1 to 10.0 μg L−1).
The standard deviation of (3.5%), and detection limit of the method (2.2 μg L−1 in time 50 sec, 285 nm) were
obtained for sensor level response PbS Quantum Dot–Gelatin Nano composites sensor with (95%) confidence
evaluated. The observed outcomes confirmed the suitability recovery and a very low detection limit for measuring
the (MNZ) drug. The method fluorometric introduced to measure (MNZ) drug in real samples such as urine and
blood was used and can be used for hospital samples. The chemical PbS Quantum Dot–Gelatin Nano composites
sensor made it possible as an excellent sensor with good reproducibility
Keywords :
Metronidazole Drug , Fluorescence , Sensor , PbS with Gelatin Synthesis , Quantum Dots
Journal title :
Iranian Journal of Analytical Chemistry