Author/Authors :
hakimi saryazdi, fatemeh payame noor university - department of chemistry, tehran, iran , hakimi saryazdi, fatemeh payame noor university - research center of environmental chemistry, ardakan, iran , golrasan, elham payame noor university - department of chemistry, tehran, iran , golrasan, elham payame noor university - research center of environmental chemistry, ardakan, iran , heidari, somaya payame noor university - department of chemistry, tehran, iran , heidari, somaya payame noor university - research center of environmental chemistry, ardakan, iran
Abstract :
in this work, a green and effective method for the synthesis of pyrazole derivatives by the reaction of a pot of various 1,3-dicarbonyl compounds with hydrazine is proposed using graphene oxide nanoparticles as the lewis base catalyst. advantages this methods are high yields, perform quick reactions, easy customization, and short-term reaction. the catalyst was recycled several times. the recycled catalyst was reused without any apparent performance drop in subsequent reactions. this process provided not only self-condensation but also cross-condensation by using the hydra-friendly nuclear reaction of hydrazines and high-efficiency, multisubstituted pyrazoles were formed under good and easy conditions.
Keywords :
one , pot reaction , nano graphene oxide , pyrazoles , green chemistry
