anticancer activity of new 3-secondary amine derivatives containing fused rings of the imidazopyridine

l2 promoted one-pot protocol was suggested previously for the synthesis of 2-aryl-3-(pyridine-2- ylamino)imidazo[1,2-a]pyridine from 2-aminopyridine with different substituted acetophenone for the synthesis of secondary amine derivatives (a1-a6) compounds. after that, the secondary amine derivatives are reacted with propargyl bromide producing propargylamines (b1-b6) compounds. all synthesized compounds were characterized via ft-ir spectroscopy, some of which were characterized by 1h-nmr spectroscopy and ^13c-nmr spectroscopy. two of imidazo(1,2-a) pyridine derivatives were tested for cytotoxic activity against leukaemia cancer using mtt assay.