Author/Authors :
martinez-resendez, michel autonomous university of nuevo leon - university hospital ‘dr. josé eleuterio gonzález’ - department of internal medicine, monterrey, mexico , martinez-resendez, michel xe1;lez , mexico , martinez-resendez, michel autonomous university of nuevo leon, mexico , martinez-resendez, michel xf3;n, mexico , cruz-lópez2, flora autonomous university of nuevo leon - school of chemistry - department of pharmaceutical biological chemistry, nuevo león, mexico , gaona-chávez, natalia autonomous university of nuevo leon - university hospital ‘dr. josé eleuterio gonzález’ - department of internal medicine, monterrey, mexico , camacho-ortiz, adrián autonomous university of nuevo leon - university hospital ‘dr. josé eleuterio gonzález’ - department of internal medicine, monterrey, mexico , mercado-longoria, roberto autonomous university of nuevo leon - university hospital ‘dr. josé eleuterio gonzález’ - department of internal medicine, monterrey, mexico , mercado-longoria, roberto xe1;lez , mexico , mercado-longoria, roberto autonomous university of nuevo leon, mexico , mercado-longoria, roberto xf3;n, mexico , bocanegra-ibarias, paola autonomous university of nuevo leon - university hospital ‘dr. josé eleuterio gonzález’ - department of internal medicine, monterrey, mexico , bocanegra-ibarias, paola xe1;lez , mexico , bocanegra-ibarias, paola autonomous university of nuevo leon, mexico , bocanegra-ibarias, paola xf3;n, mexico , flores-treviño, samantha autonomous university of nuevo leon - university hospital ‘dr. josé eleuterio gonzález’ - department of internal medicine, monterrey, mexico , garza-gonzález, elvira autonomous university of nuevo leon - school of medicine, university hospital‘dr. josé eleuterio gonzález’ - department of biochemistry and molecular medicine, monterrey, mexico
Abstract :
background and objectives: measures to prevent the emergence of hospital-acquired infections (hais) include a daily bath with chlorhexidine gluconate (chg). the aim of this study was to determine the effect of patients bathing daily with chg on the bacterial colonization on patient surfaces, environmental surrounding areas, and attending healthcare workers (hcws). materials and methods: patients were randomized by a 1:1 in two groups. patients in group 1 were bathed daily with chg; patients in group 2 were bathed with a placebo. microbiological sampling of patients, environment, and hcws were carried out on days 0, 3, and 10. the clonal relatedness of selected isolates collected was determined through pulsed-field gel elec- trophoresis. clinical and demographic data were obtained from medical files. results: thirty-three patients were included (18 in group 1 and 15 in group 2). the more common species was acinetobacter baumannii (n=144), followed by klebsiella pneumoniae (n=81). a. baumannii was isolated more frequently on environmen- tal surfaces in group 2 than group 1 (day 0 vs. day 3 vs. day 10; p = 0.0388). twelve clones of a. baumannii were detected, with predominant clone a detected in patients and environmental surfaces. no pathogens were detected in hcws. conclusion: our data support that chg bathing decreases a. baumannii surviving on the environmental surfaces of criti- cally ill patients.
Keywords :
infection disease transmission , chlorhexidine , decontamination , acinetobacter baumannii , gram , negative bac , teria
