Congenital Brain Tumors, A Series of Seven Patients

Objective: Congenital brain tumors are very rare. We review these tumors in patients younger than 2 months diagnosed in our Department.Material Methods: Seven congenital brain tumors were diagnosed during five years. Clinicaland radiological findings and prognosis are analyzed.Findings: The study included 5 female and two male infants. Two cases were diagnosedantenatally by means of ultrasonography. All patients presented with intracranial hypertension.The tumor was non-homogenous with cystic and solid components in all neuroimaging, exceptfor the case with choroid plexus papilloma. Hydrocephalus was evident in all of them. Mostfindings were infra-tentorial lesions. There were three teratomas, one primitive neuro-ectodermaltumor, one ependymoblastoma and one choroid plexus papilloma. Six patients were operated on,with one intra-operative death. Two passed away postoperatively with aspiration pneumonia.One patient died due to complications of chemotherapy and another one due to tumor recurrenceone year after surgery. Only the patient with choroid plexus papilloma is alive after 2 years.Conclusion: Today, the availability of noninvasive imaging procedures such as computerizedtomography scan and magnetic resonance imaging has improved the diagnosis of congenitalbrain tumors. Inspite of development in prenatal diagnosis, appropriate pre and post operativemanagement, the mortality associated with these tumors still remains high. The final prognosisin these patients is still discouraging despite early surgery and operative and anestheticimprovements. Choroid plexus papilloma accompanies the best prognosis, whereas teratoma andprimitive neuroectodermal tumors have the worst prognosis.