A Novel Variation in Fischer Indole Reaction for Viable and Rapid Synthesis of 1,2,3,4-Tetrahydro-6,8-Dinitro-9H-Carbazole

A very stimulating variation in Fischer indole reaction by adopting solvent and catalyst free conditions is reported in this work. A concise synthesis of dinitro tetrahydrocarbazole derivative 3 was introduced without using any accelerating agent at ambient temperature with fairly good yield. This procedure has been actually reported for the first time within this work. Additionally, the validity of product was fully corroborated by the obtained characterizing results from the employed spectroscopic techniques such as ultra violet (UV), Fourier transform infrared (FT-IR) and proton and carbon nuclear magnetic resonance (1H and 13C NMR), Mass spectrometer (MS) and carbon, hydrogen and nitrogen (CHN) analyzer. And finally, it could be mentioned that the investigated reaction could be equally run without use of any catalyst as a favorable approach to adopt Green Chemistry.