Histopathological changes caused by noise exposure in lung, heart, kidney, and liver tissues in New Zealand white rabbits

Introduction: Noise exposure is a common phenomenon in all personal life activities. Due to the prevalence of exposure to noise, many people are exposed to noise. Some of the harmful effects of noise on human health have been proven so far. The purpose of this study was to experiment histopathological effects caused by exposure to white noise. Materials and methods: Four New Zealand white rabbits were exposed to 85±2 dB white noise for five consequent days. Heart, kidney, liver, and lung tissues were studied by the Hematoxylin and Eosin staining (H&E) method. The independent t-test was used for comparing the mean weight of tissues. Results: This study showed that exposure to 85±2 dB white noise did not significantly change heart and lungs tissues. Nevertheless, this study indicated that exposure to noise induced different pathological changes in kidney and liver tissues. Exposure to noise made congestion, unclear brush border, and tubular cell vacuolization in kidney tissue. Moreover, eosinophilic cytoplasm was made by noise exposure in liver tissue. Furthermore, no statistically significant difference was detected in the mean tissue weight/mean body weight in rabbits. Conclusion: This study showed that exposure to noise might be a risk factor for different renal and hepatic diseases. Nevertheless, more studies need to complete these results.