Author/Authors :
Bajic, Biljana Health Promotion Center - Institute of Public Health Montenegro - Podgorica, Montenegro , Galic, Igor Center for Control and Prevention of Noncommunicable Diseases - Institute for Public Health Montenegro - Podgorica, Montenegro , Mihailovic, Natasa Department of Biostatistics and Informatics - Institute of Public Health Kragujevac - Kragujevac, Serbia , Ristic, Svetlana Institute for Oncology and Radiology of Serbia - Belgrade, Serbia , Radevic, Svetlana Department of Social Medicine - Faculty of Medical Sciences - University of Kragujevac - Kragujevac, Serbia , Iric Cupic, Violeta Department of Internal Medicine - Faculty of Medical Sciences - University of Kragujevac - Kragujevac, Serbia , Kocic, Sanja Department of Social Medicine - Faculty of Medical Sciences - University of Kragujevac - Kragujevac, Serbia , Arnaut, Aleksandra Department of Dentistry - Faculty of Medical Sciences - University of Kragujevac - Kragujevac, Serbia
Abstract :
Background: Comorbidities are major predictors of in-hospital mortality in stroke patients. The Charlson comorbidity index (CCI) and the Elikhauser comorbidity index (ECI) are scoring systems for classifying comorbidities. We aimed to compare the performance of the CCI and ECI to predict in-hospital mortality in stroke patients.
Methods: We included patients hospitalized for stroke in the Clinical Center of Kragujevac, Serbia for the last 7 years. Hospitalizations caused by stroke, were identified by the International Classification of Diseases-10 (ICD-10) codes I60.0 - I69.9. All patients were divided into two cohorts: Alive cohort (n=3297) and Mortality cohort (n=978).
Results: There were significant associations between higher CCIS and increased risk of in-hospital mortality (HR = 1.07, 95% CI = 1.01–1.12) and between higher ECIS and increased risk of in-hospital mortality (HR = 1.04, 95% CI = 0.99–1.09). Almost 2/3 patients (66.9%) had comorbidities included in the CCI score and 1/3 patients (30.2%) had comorbidities included in the ECI score. The statistically significant higher CCI score (t = -3.88, df = 1017.96, P <0.01) and ECI score (t = -6.7, df = 1447.32, P <0.01) was in the mortality cohort.
Area Under the Curve for ECI score was 0.606 and for CCI score was 0.549.
Conclusion: Both, the CCI and the ECI can be used as scoring systems for classifying comorbidities in the administrative databases, but the model’s ECI Score had a better discriminative performance of in-hospital mortality in the stroke patients than the CCI Score model.
Keywords :
Stroke , In-hospital mortality , Charlson comorbidity index , Elixhauser comorbidity index
