Title of article
Development of Progressive Chiari I Malformation in a Child with Unilateral Sporadic Retinoblastoma
Author/Authors
Karimi, Saeed Ophthalmic Research Center - Research Institute for Ophthalmology and Vision Science - Shahid Beheshti University of Medical Sciences, Tehran, Iran - Department of Ophthalmology - Torfeh Medical Center - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Arabi, Amir Department of Ophthalmology - Torfeh Medical Center - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Shahraki, Toktam Department of Ophthalmology - Torfeh Medical Center - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Ansari, Iman Department of Ophthalmology - Torfeh Medical Center - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Safi, Sare Ophthalmic Epidemiology Research Center - Research Institute for Ophthalmology and Vision Science - Shahid Beheshti University of Medical Sciences, Tehran, Iran
Pages
3
From page
88
To page
90
Abstract
Purpose: To report a case of progressive Chiari malformation type I (CIM) in a patient with unilateral sporadic retinoblastoma (RB) treated with intra‑arterial chemotherapy (IAC) and enucleation.
Methods: A 5‑year‑old male patient with a history of RB in his left eye treated with IAC and enucleation presented to our clinic for routine
RB surveillance. Radiotherapy had not been used for the treatment of his RB.
Results: A progressive herniation of cerebellar tonsils through the foramen magnum was detected on follow‑up magnetic resonance
imaging (MRI). Brain and cervical MRI revealed no central nervous system mass, hydrocephalus, or syringomyelia. There was no history of head trauma.
Conclusion: Progressive CIM may occur in unilateral sporadic RB.
Keywords
Chiari malformation , Chiari malformation type I , Germline , Intra‑arterial chemotherapy , Posterior fossa , Retinoblastoma , Sporadic
Journal title
Journal of Current Ophthalmology
Serial Year
2021
Record number
2715425
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