Title of article :
Successful Treatment of Unremitting Gastro-Intestinal Hemorrhage and Rashes of Henoch-Schönlein Purpura with Colchicine & Cryoprecipitate: A Case Report and Literature Review
Author/Authors :
Huque, Saimul Bangabandhu Sheikh Mujib Medical University , Amaan, Abdullahel Bangabandhu Sheikh Mujib Medical University , Mamun, Abdullah-Al Bangabandhu Sheikh Mujib Medical University , Jesmin, Tahmina Bangabandhu Sheikh Mujib Medical University , Begum, Afroza Bangabandhu Sheikh Mujib Medical University , Ranjan Roy, Ranjit Bangabandhu Sheikh Mujib Medical University , Muin Uddin, Golam Bangabandhu Sheikh Mujib Medical University
Abstract :
Severe gastrointestinal manifestations and rashes of Henoch Schonlein Purpura (HSP) may not always respond to prednisolone or another immunosuppressive agent. Though reduced factor XIII may play a role in gastrointestinal manifestations but its role in management of skin rashes is uncertain. Here, we reported a case treated with different immunosuppressive agents but didn`t respond. Thereafter, despite having the normal factor XIII assay, the unremitting GI symptoms and skin rashes, has improved after prescribing colchicines & infusion of Cryoprecipitate containing factor XIII.
Keywords :
HSP , Gastrointestinal Bleeding , Rash , Cryoprecipitate , Colchicine
Journal title :
Journal of Pediatric Nephrology
