Author/Authors :
Esfandiar, Nasrin Mofid Children's Hospital - Pediatric Nephrology Research Center - Research Institute for Children's Health - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Khalili, Mitra Department of Radiology - School of Medicine - Mofid Children's Hospital - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Dalirani, Reza Mofid Children's Hospital - Pediatric Nephrology Research Center - Research Institute for Children's Health - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Nickhoo, Zohreh School of Medicine - Pediatric Nephrology Research Center - Mofid Children's Hospital - Shahid Beheshti University of Medical Sciences, Tehran, Iran
Abstract :
Background and aims: Contrast-induced renal impairment endangers the patients' health and imposes a financial burden on families and the health care system. Therefore, this study was conducted to examine the rate of nephropathy in patients admitted to Mofid Children's Hospital in 2018 and 2019. Methods: In this cross-sectional study serum creatinine was measured at baseline and 48-72 hours after CT-scan an increase of more than 25% in serum creatinine was considered CIN. Paired sample t-test was used to assess the change in the Cr. The research data were analyzed using SPSS-25 software and the significance level in all tests was set at P = 0.001. Results: In this study, 180 children underwent contrast-enhanced CT-scan with a mean age of 5.72 years, of whom 81 (45%) were girls and 99 (55%) were boys. The mean baseline creatinine was 0.633 ± 0.137 mg / dl, which increased significantly to 0.675± 0.164 mg / dl 48-72 hours after the first measurement. The chance of developing ARF in ciprofloxacin users was 4.86 times higher than patients who did not use this drug. Conclusion: In children underwent CT scan, the incidence of ARF is 17.2%. Ciprofloxacin increases the risk of acute kidney problems by 4.8 times.
Keywords :
Acute Kidney Injury , Contrast Nephropathy , Ciprofloxacin , Child
