Title of article :
Enantioselective Copper-catalysed Conjugate Addition of Diphenylzinc to Cyclohexenone
Author/Authors :
Wu, Xiao-yu Chinese Academy of Sciences - Shanghai Institute of Organic Chemistry - State Key Laboratory of Organometallic Chemistry, China , Li, Xiang-guo Chinese Academy of Sciences - Shanghai Institute of Organic Chemistry - State Key Laboratory of Organometallic Chemistry, China , Zhao, Gang Chinese Academy of Sciences - Shanghai Institute of Organic Chemistry - State Key Laboratory of Organometallic Chemistry, China
Abstract :
The copper-catalysed asymmetric conjugate addition of diphenylzinc to 2-cyclohexenone has been carried out with good results. An enantiometric excess of up to 91% was obtained using 5 mol% CuI and 5 mol% phosphine ligand derived from L-proline.
Keywords :
Copper , catalyzed , conjugate , addition , diphenylzinc , phosphine , ligand
Journal title :
letters in organic chemistry
Journal title :
letters in organic chemistry
