Title of article
One-Pot, Regioselective Synthesis of 1,3,5 Trisubstituted Hydantoins byDomino Condensation/aza-Michael/OــــN acyl Migration of AsymmetricCarbodiimides with α,β-Unsaturated Carboxylic Acids
Author/Authors
Volonterio, Alessandro Materiali ed Ingegneria Chimica “G. Natta” del Politecnico di Milano - Dipartimento di Chimica, Italy , Zanda, Matteo C.N.R. - Istituto di Chimica del Riconoscimento Molecolare - sezione “A Quilico”, Italy
From page
44
To page
46
Abstract
1,3,5 Trisubstituted hydantoins having two different substituents at the nitrogen atoms could besmoothly prepared by a domino condensation/aza-Michael/OــــN acyl migration of asymmetric carbodiimides with activated α,β-unsaturated carboxylic acids. The regiochemical outcome of the process, as well as scope and limits, are discussed.
Keywords
Hydantoins , domino reaction , aza , Michael , carbodiimides , regiochemistry
Journal title
letters in organic chemistry
Journal title
letters in organic chemistry
Record number
2717808
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