Title of article
Influence of Homoallylic Fluorine Atoms on the Regioselectivity of theWacker Reaction
Author/Authors
Guidotti, J. Université de Versailles - UMR CNRS - SIRCOB, France , Tordeux, M. Université de Versailles - UMR CNRS - SIRCOB, France , Blazejewski, J.-C. Université de Versailles - UMR CNRS - SIRCOB, France , Wakselman, C. Université de Versailles - UMR CNRS - SIRCOB, France
From page
148
To page
150
Abstract
Wacker oxidation reaction of terminal olefins bearing one or two fluorine atoms at a homoallylic position led to a ratio aldehyde/methyl ketone much higher than that observed with their non-fluorinated analogues. This regioselectivity can be ascribed to a specific interaction between fluorine atoms and palladium, or to a peculiar influence of the halogens on the double bond.
Keywords
Wacker reaction , palladium , fluorine , regioselectivity
Journal title
letters in organic chemistry
Journal title
letters in organic chemistry
Record number
2717813
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