Title of article
A Facile Synthesis of Chiral Isocyanate-phenol and Unsymmetrical Urea Derived from Tyrosines without Protecting Phenolic Hydroxyl Groups
Author/Authors
Nagai, Atsushi Yamagata University - Faculty of Engineering - Department of Polymer Science and Engineering, Japan , Ochiai, Bungo Yamagata University - Faculty of Engineering - Department of Polymer Science and Engineering, Japan , Endo, Takeshi Yamagata University - Faculty of Engineering - Department of Polymer Science and Engineering, Japan
From page
404
To page
406
Abstract
A facile method for synthesis and isolation of chiral isocyanate-phenols, obtained from the reactions of L-tyrosine and L-DOPA [L-3-(3,4-dihydroxyphenyl)alanine] derivatives with di-tert-butyltricarbonate(DBTC), is described. Reaction of the obtained isocyanate-phenol with n-butylamine gave the correspondingchiral unsymmetrical urea
Keywords
Isocyanate , phenol , unsymmetrical , urea , tyrosine , DOPA , di , tert , butyltricarbonate
Journal title
letters in organic chemistry
Journal title
letters in organic chemistry
Record number
2717876
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