Title of article :
Diastereoselective Allylation of Imines with (gamma)-Silyloxyallylstannanes Promoted by Trimethylsilyl Triflate and Application to the Synthesis of Erythro-Sphingosine
Author/Authors :
Shimizu, Makoto Mie University - Department of Chemistry for Materials, Japan , Ando, Hiromi Mie University - Department of Chemistry for Materials, Japan , Niwa, Yasuki Mie University - Department of Chemistry for Materials, Japan
Abstract :
Addition of g-silyloxyallylstannanes to imines in the presence of trimethylsilyl triflate was studied.Allylation of a-imino ester with (Z)-allylstannane proceeded to give anti-adduct as a major product, which was transformed into N,O,O-triacetyl erythro-sphingposine via appropriate functional group transformations.
Keywords :
gamma , Silyloxyallylstannane , Imines , Allylation , erythro , Sphingosine.
Journal title :
letters in organic chemistry
Journal title :
letters in organic chemistry
