Author/Authors :
Yang, Wen-Wei Chengdu Institute of OrganicChemistry Chinese Academy of Sciences Chengdu - Key Laboratory for Asymmetric Synthesis and Chirotechnology of Sichuan Province, China , Yang, Wen-Wei Graduate School of Chinese Academy of Sciences, China , Cun, Lin-Feng Chengdu Institute of OrganicChemistry Chinese Academy of Sciences Chengdu - Key Laboratory for Asymmetric Synthesis and Chirotechnology of Sichuan Province, China , Cun, Lin-Feng Graduate School of Chinese Academy of Sciences, China , Zhi, Yong-Gang Chengdu Institute of OrganicChemistry Chinese Academy of Sciences Chengdu - Key Laboratory for Asymmetric Synthesis and Chirotechnology of Sichuan Province, China , Zhi, Yong-Gang Graduate School of Chinese Academy of Sciences, China , Mi, Ai-Qiao Chengdu Institute of OrganicChemistry Chinese Academy of Sciences Chengdu - Key Laboratory for Asymmetric Synthesis and Chirotechnology of Sichuan Province, China , Mi, Ai-Qiao Graduate School of Chinese Academy of Sciences, China , Jiang, Yao-Zhong Chengdu Institute of OrganicChemistry Chinese Academy of Sciences Chengdu - Key Laboratory for Asymmetric Synthesis and Chirotechnology of Sichuan Province, China , Jiang, Yao-Zhong Graduate School of Chinese Academy of Sciences, China , Gong, Liu-Zhu Chengdu Institute of Organic Chemistry Chinese Academy of Sciences Chengdu - Key Laboratory for Asymmetric Synthesis and Chirotechnology of Sichuan Province, China , Gong, Liu-Zhu Graduate School of Chinese Academy of Sciences, China
Abstract :
The use of easily accessible N-monosubstituted 1,2-diphenyl-2-aminoethanols as ligands topromote the asymmetric addition of diethylzinc to alkyl- and arylimines generated in situ from the precursors provided optically active N-diphenylphosphinylamines with enantioselectivities of up to 96% ee.
Keywords :
Asymmetric catalysis , amino alcohols , diethylzinc addition , imines
