Author/Authors :
Pang, Heungwing The University of Hong Kong - Department of Chemistry, China , Xu, Zhengshuang The University of Hong Kong - Department of Chemistry, China , Xu, Zhengshuang The Peking University - Shenzhen Graduate School - Laboratory of Chemical Genomics, China , Chen, Zhiyong The University of Hong Kong - Department of Chemistry, China , Ye, Tao The University of Hong Kong - Department of Chemistry, China , Ye, Tao The Hong Kong Polytechnic University - Department of Applied Biology Chemical Technology, China
Abstract :
The total synthesis of lyngbyabellin A, a biologically active metabolite from the marine cyanobacterium Lyngbya majuscula, is reported. There is flexibility in the approach which can readily allow structural modifications to be introduced.
Keywords :
Cyanobacterium , L. majuscula , synthesis , natural product , macrocyclisation , peptolide