Title of article :
KF/Al2O3 Mediated Aza-Michael Addition of Indoles to Electron-Deficient Olefins
Author/Authors :
Matloubi Moghaddam, Firouz sharif university of technology - Department of Chemistry, تهران, ايران , Rezanejade Bardajee, Ghasem sharif university of technology - Department of Chemistry, تهران, ايران , DokhtTaimoory, Maryam sharif university of technology - Department of Chemistry, تهران, ايران
Abstract :
KF/Al2O3 efficiently catalyzes aza-Michael addition of indole and 3-methylindole to a variety ofelectron-deficient conjugated alkenes such as a,b-unsaturated ketones, amides and nitriles. The N-alkylationadducts are produced in good to excellent yields and relatively in short times. The catalyst can be recycled for subsequent reactions without any appreciable loss of efficiency.
Keywords :
KF , Al2O3 , aza , Michael addition , N , alkylation , Indole , Electron , deficient olefins
Journal title :
letters in organic chemistry
Journal title :
letters in organic chemistry
