Title of article
K2CO3-Mediated Regioselective Synthesis of Isoxazoles and Pyrazolines
Author/Authors
Kidwai, Mazaahir University of Delhi - Department of Chemistry, India , Kukreja, Shuchi University of Delhi - Department of Chemistry, India , Thakur, Ruby University of Delhi - Department of Chemistry, India
From page
135
To page
139
Abstract
3,5-Diarylisoxazoles and 1,3,5-triarylpyrazolines are synthesized via Michael addition of“hydroxylamine hydrochloride, phenylhydrazine” respectively over chalcones followed by cyclizationusing K2CO3 as solid support. Reactions are shown to be highly regioselective regardless of the nature of the substituent in the substrates and afforded single isoxazole and pyrazoline isomer in excellent yields.
Keywords
Michael addition , regioselectivity , chalcones , solid support
Journal title
letters in organic chemistry
Journal title
letters in organic chemistry
Record number
2717975
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