Title of article :
One-Pot Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones Using Hydrochloric Acid- β-Cyclodextrin-Combined Catalysts
Author/Authors :
Zhou, Haixia Liaoning University of Petroleum and Chemical Technology - Department of Chemistry, China , He, Miao Liaoning University of Petroleum and Chemical Technology - Department of Chemistry, China , Liu, Chunsheng Liaoning University of Petroleum and Chemical Technology - Department of Chemistry, China , Luo, Genxiang Liaoning University of Petroleum and Chemical Technology - Department of Chemistry, China
Abstract :
An improved approach has been found to carry out the Biginelli reaction for the synthesis of 3,4-dihydropyrimidin- 2(1H)-one derivatives. This synthesis was performed in the presence of hydrochloric acidand b-cyclodextrin in ethanol solution. Compared with the classical Biginelli reaction conditions, this new approach has the advantage of excellent yields and short reaction time
Keywords :
Biginelli reaction , Dihydropyrimidinones , b , cyclodextrin , One , pot , Synthesis
Journal title :
letters in organic chemistry
Journal title :
letters in organic chemistry
