Title of article :
Convergent Synthetic Studies Towards the Ribosyl-Diazepanone Core of the Liposidomycins
Author/Authors :
Bourdreux, Yann Université de Versailles St-Quentin-en-Yvelines - Institut Lavoisier de Versailles, France , Drouillat, Bruno Université de Versailles St-Quentin-en-Yvelines - Institut Lavoisier de Versailles, France , Greck, Christine Université de Versailles St-Quentin-en-Yvelines - Institut Lavoisier de Versailles, France
Abstract :
New types of ribosyl-diazepanone derivatives of nucleoside antibiotic liposidomycins, 12a and12b, have been synthesised. The ribosyl 7-membered heterocycles were formed by reductive amination of thea-ribosylamino acid 9 derived from D-ribose and the amino aldehydes 10a or 10b, followed by a peptidiccoupling reaction.
Keywords :
Antibiotic , diazepanone , lactamisation , liposidomycin , ribosylamino acid
Journal title :
letters in organic chemistry
Journal title :
letters in organic chemistry
