Title of article :
Oxepin- and Spiro-Annulation of 2-Pyridone in Conjunction with Claisen Rearrangement and Ruthenium Carbene Complex Mediated Enyne Metathesis
Author/Authors :
Majumdar, Krishna C. University of Kalyani - Department of Chemistry, India , Rahaman, Habibur University of Kalyani - Department of Chemistry, India , Roy, Brindaban University of Kalyani - Department of Chemistry, India
Abstract :
A direct synthesis of substituted oxepin and spiroheterocycles has been achieved from substrates derived from 4-hydroxy-1,6-dimethyl pyridine-2-ones (1) by combining Claisen rearrangement and ring closing enyne metathesis. The RCEM proceeded smoothly under nitrogen atmosphere at room temperature in the presence of well-defined ruthenium catalyst A (10 mol%).
Keywords :
2 , Pyridone , oxepin , ring , closing metathesis , Claisen rearrangement , enyne metathesis
Journal title :
letters in organic chemistry
Journal title :
letters in organic chemistry
